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    GLP Drug Comparison

    Which GLP-1 is Right for You?

    Compare Semaglutide, Tirzepatide, and Retatrutide based on your tolerance and goals.

    Click any option for a complete deep dive

    Semaglutide

    Ozempic, Wegovy

    beginner
    Intensity
    Tolerability

    The gentle starter

    Reduces appetite and slows digestion for steady fat loss while protecting muscle

    Metabolic Scope

    GLP-1 only: satiety and insulin sensitivity

    Best For

    • First-time GLP users
    • Moderate fat loss goals
    • Good tolerance to side effects
    • Maintaining muscle while cutting
    Tirzepatide

    Mounjaro, Zepbound

    intermediate
    Intensity
    Tolerability

    The fast track

    Dual-action appetite control with enhanced fat loss - more powerful but requires attention to muscle protection

    Metabolic Scope

    GLP-1 + GIP: deeper metabolic rebalancing with improved nutrient partitioning

    Best For

    • Experienced with appetite suppressants
    • Want faster results than semaglutide
    • Willing to be disciplined with support protocols
    • Type 2 diabetes or sleep apnea
    Retatrutide

    Investigational (Phase 2)

    advanced
    Intensity
    Tolerability

    The heavy hitter

    Triple-action for maximum fat loss - requires meticulous muscle protection and supervised approach

    Metabolic Scope

    GLP-1 + GIP + Glucagon: whole-system metabolic rewiring with enhanced fat oxidation

    Best For

    • Advanced users with GLP experience
    • Willing to be extremely disciplined
    • Have muscle protection protocols dialed
    • Want maximum fat loss results